Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728442 | 0.85 | EGLN1 (0.40) | ALDH1A1EGLN1ERCC1ERCC4SMN1; SMN2 | |
| SCHEMBL7837188 | 0.84 | DDB1 (0.56) | SIGMAR1SMN1; SMN2DDB1CRBNL3MBTL1 | |
| SCHEMBL30109416 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EKCNH2SIGMAR1SMN1; SMN2 | |
| SCHEMBL8363891 | 0.74 | ERCC1 (0.48) | ALDH1A1P2RX7ERCC1ERCC4KCNH2 | |
| SCHEMBL8540645 | 0.72 | GAA (0.55) | ALDH1A1GRM2SIGMAR1SMN1; SMN2 | |
| SCHEMBL10399987 | 0.71 | L3MBTL1 (0.67) | ALDH1A1ERCC1ERCC4KDM4EKCNH2 | |
| SCHEMBL6936734 | 0.71 | ALOX5 (0.43) | DRD3L3MBTL1HPGD | |
| SCHEMBL4141868 | 0.71 | ERCC1 (0.44) | ALDH1A1P2RX7ERCC1ERCC4KDM4E | |
| SCHEMBL15038459 | 0.71 | ERCC1 (0.54) | ALDH1A1P2RX7ERCC1ERCC4KDM4E | |
| SCHEMBL13924866 | 0.70 | ERCC1 (0.50) | ALDH1A1P2RX7ERCC1ERCC4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362441-B1 | SELECTIVE NR2B ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-12 | — | — | EP | disclosed |