Sugi Predict

Sugi Predict / Compounds / SCHEMBL2233396

SCHEMBL2233396

SCHEMBL2233396

COC[C@@H](NC(=O)OCc1ccccc1)C(=O)NCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 1/20 0.71
▸ CA1 P00915 1/20 0.71
▸ CA2 P00918 1/20 0.71
▸ CA3 P07451 1/20 0.71
▸ CA4 P22748 1/20 0.71
▸ CA6 P23280 1/20 0.71
▸ CA5A P35218 1/20 0.71
▸ CA7 P43166 1/20 0.71
▸ CACNA1C Q13936 1/20 0.71
▸ SCN9A Q15858 1/20 0.71
▸ CA9 Q16790 1/20 0.71
▸ CA13 Q8N1Q1 1/20 0.71
▸ CA14 Q9ULX7 1/20 0.71
▸ CA5B Q9Y2D0 1/20 0.71
▸ CTSS P25774 6/20 0.60
▸ CTSL P07711 5/20 0.60
▸ CTSK P43235 5/20 0.60
▸ CTSB P07858 3/20 0.60
▸ MAPT P10636 2/20 0.57
▸ GAA P10253 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2236257 1.00 CA12 (0.71) CA12CA1CA2CA3CA4
SCHEMBL993388 0.96 CA12 (0.67) CA12CA1CA2CA3CA4
SCHEMBL12210093 0.91 CA12 (0.60) CA12CA1CA2CA3CA4
SCHEMBL992795 0.90 CA12 (0.59) CA12CA1CA2CA3CA4
SCHEMBL18721571 0.90 CA12 (0.71) CA12CA1CA2CA3CA4
SCHEMBL13583868 0.90 CA12 (0.71) CA12CA1CA2CA3CA4
SCHEMBL13583863 0.90 CA12 (0.71) CA12CA1CA2CA3CA4
SCHEMBL2303306 0.88 CA12 (0.70) CA12CA1CA2CA3CA4
SCHEMBL2303305 0.88 CA12 (0.70) CA12CA1CA2CA3CA4
SCHEMBL12188303 0.88 CA12 (0.57) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130041180-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES PRIVATE LIMITED (IN) 2013-02-14 — — US claimed
EP-2534127-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN Laboratories Limited (IN) 2012-12-19 — — EP claimed
WO-2011099033-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE MSN LABORATORIES LIMITED (IN) 2011-08-18 — — WO claimed
US-20100240926-A1 PROCESS FOR PREPARING (R)-N-BENZYL-2-(BENYLOXYCARBONYLAMINO)-3-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — US claimed
EP-3144295-A1 PROCESS FOR THE PREPARATION OF LACOSAMIDE Divi's Laboratories Limited (IN) 2017-03-22 — — EP disclosed
EP-2444390-B1 Process for producing Lacosamide EUTICALS GMBH (DE) 2017-02-01 — — EP disclosed
US-9447024-B1 Process for the preparation of lacosamide DIVI'S LABORATORIES LIMITED (IN) 2016-09-20 — — US disclosed
US-8957252-B2 Process for preparation of lacosamide and some N-benzyl-propanamide intermediate derivatives INDOCO REMEDIES LIMITED (IN) 2015-02-17 — — US disclosed
US-8907132-B2 Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide MSN LABORATORIES PRIVATE LIMITED (IN) 2014-12-09 — — US disclosed
US-8907132-B2 Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide MSN LABORATORIES PRIVATE LIMITED (IN) 2014-12-09 — — US disclosed
US-8829226-B2 Lacosamide intermediate compound, preparation method thereof and use thereof ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) 2014-09-09 — — US disclosed
US-8759582-B2 Process for the preparation of lacosamide NATCO PHARMA LIMITED (IN) 2014-06-24 — — US disclosed
WO-2010107993-A3 PROCESS FOR PREPARING (R)-7V-BENZYL-2- (BENYLOXYCARBONYLAMINO)-S-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-11-04 — — WO disclosed
WO-2010107993-A2 PROCESS FOR PREPARING (R)-7V-BENZYL-2- (BENYLOXYCARBONYLAMINO)-S-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — WO disclosed
WO-2010107993-A2 PROCESS FOR PREPARING (R)-7V-BENZYL-2- (BENYLOXYCARBONYLAMINO)-S-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — WO disclosed
WO-2010107993-A2 PROCESS FOR PREPARING (R)-7V-BENZYL-2- (BENYLOXYCARBONYLAMINO)-S-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — WO disclosed
US-20100240926-A1 PROCESS FOR PREPARING (R)-N-BENZYL-2-(BENYLOXYCARBONYLAMINO)-3-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — US disclosed
US-20100240926-A1 PROCESS FOR PREPARING (R)-N-BENZYL-2-(BENYLOXYCARBONYLAMINO)-3-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — US disclosed
US-20100240926-A1 PROCESS FOR PREPARING (R)-N-BENZYL-2-(BENYLOXYCARBONYLAMINO)-3-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — US disclosed
US-20100240926-A1 PROCESS FOR PREPARING (R)-N-BENZYL-2-(BENYLOXYCARBONYLAMINO)-3-METHOXYPROPIONAMIDE PLIVA HRVATSKA D.O.O. (HR) 2010-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240926-A1 PROCESS FOR PREPARING (R)-N-BENZYL-2-(BENYLOXYCARBONYLAMINO)-3-METHOXYPROPIONAMIDE NAAA, MME, CA2 CA12 217/4885CA1 76/4885CA2 3/4885
US-20130041180-A1 PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE AMY1A, PTMA, NAAA CA12 3088/4885CA1 1930/4885CA2 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.