Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22333924 | 1.00 | ADRB1 (0.47) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL22333925 | 1.00 | ADRB1 (0.47) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL23982125 | 1.00 | ADRB1 (0.47) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL24687180 | 1.00 | ADRB1 (0.47) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL24690089 | 0.88 | MAOB (0.40) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL594778 | 0.85 | ADK (0.45) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL594779 | 0.85 | ADK (0.45) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL23982318 | 0.82 | ADRB1 (0.46) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL11915452 | 0.82 | ADRB1 (0.49) | ADRB1DNMT1LMNASMN1; SMN2TK1 | |
| SCHEMBL1799615 | 0.82 | ADRB1 (0.46) | ADRB1DNMT1LMNASMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692996-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE | Immune Sensor, LLC (US) | 2020-08-12 | — | — | EP | disclosed |