Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22333924 | 0.88 | ADRB1 (0.47) | MAOBADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL23982125 | 0.88 | ADRB1 (0.47) | MAOBADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL22334012 | 0.88 | ADRB1 (0.47) | MAOBADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL24687180 | 0.88 | ADRB1 (0.47) | MAOBADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL22333925 | 0.88 | ADRB1 (0.47) | MAOBADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL6914288 | 0.74 | POLB (0.62) | ADRB1DNMT1POLBLMNAPDE4D | |
| SCHEMBL317816 | 0.74 | POLB (0.62) | ADRB1DNMT1POLBLMNAPDE4D | |
| SCHEMBL594778 | 0.74 | ADK (0.45) | DUTADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL594779 | 0.74 | ADK (0.45) | DUTADRB1DNMT1LMNASMN1; SMN2 | |
| SCHEMBL11915452 | 0.73 | ADRB1 (0.49) | ADRB1DNMT1LMNASMN1; SMN2PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429596-B1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE | IMMUNE SENSOR LLC (US) | 2022-08-31 | — | — | EP | disclosed |