Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638040 | 0.88 | KMT2A (0.50) | KMT2AATMGLACNR1FPR2 | |
| SCHEMBL17916743 | 0.79 | RAB9A (0.69) | KMT2AATMCNR1FPR2ALDH1A1 | |
| SCHEMBL16562164 | 0.75 | RAB9A (0.67) | KMT2AATMCNR1FPR2ALDH1A1 | |
| SCHEMBL3452433 | 0.74 | POLB (0.68) | POLBSMN1; SMN2 | |
| SCHEMBL10921668 | 0.74 | GLA (0.59) | KMT2AGLAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16562203 | 0.74 | CNR1 (0.63) | KMT2AATMCNR1FPR2ALDH1A1 | |
| SCHEMBL16562011 | 0.73 | CNR1 (0.85) | CNR1FPR2SMN1; SMN2 | |
| SCHEMBL16562083 | 0.73 | PTPN1 (0.78) | KMT2AATMCNR1FPR2ALDH1A1 | |
| SCHEMBL637257 | 0.72 | NPC1 (0.54) | KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10923330 | 0.72 | GLA (0.59) | KMT2AGLAALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354120-A1 | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof | XenoPort, Inc. (US) | 2011-08-10 | — | — | EP | disclosed |