SCHEMBL2233478

SCHEMBL2233478

CCCC(NC(=O)OCOc1ccc(OC)cc1)c1ccc(Cl)cc1.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 11/20 0.51
FAAH O00519 2/20 0.51
CNR2 P34972 1/20 0.46
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638041 0.88 UTS2R (0.53) UTS2RFAAHCNR2POLBMAPT
SCHEMBL916706 0.75 UTS2R (0.51) UTS2RCNR2POLBMAPT
SCHEMBL637258 0.74 SMN1; SMN2 (0.45) MAPTKMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL2230625 0.72 UTS2R (0.40) UTS2RSMN1; SMN2
SCHEMBL9597125 0.72 TAS1R3 (0.48) UTS2RFAAHALDH1A1MAPK1SMN1; SMN2
SCHEMBL6684836 0.71 SMN1; SMN2 (0.48) UTS2RFAAHMEN1KMT2AL3MBTL1
SCHEMBL638108 0.70 LMNA (0.37) UTS2RL3MBTL1SMN1; SMN2
SCHEMBL3723030 0.70 SMN1; SMN2 (0.47) UTS2RFAAHMEN1KMT2AL3MBTL1
SCHEMBL2231738 0.69 UTS2R (0.42) UTS2RKMT2A
SCHEMBL1884159 0.69 SMN1; SMN2 (0.37) UTS2RCNR2POLBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2354120-A1 Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof XenoPort, Inc. (US) 2011-08-10 EP disclosed