Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362585 | 0.87 | MAOA (0.36) | — | |
| SCHEMBL8730860 | 0.82 | TDP1 (0.46) | KMT2AMEN1NPC1RAB9ACES2 | |
| SCHEMBL16085822 | 0.82 | ALDH1A1 (0.42) | CYP1A2CYP2A6TAAR1CES2CES1 | |
| SCHEMBL7197697 | 0.80 | ALDH1A1 (0.41) | KMT2AMEN1NPC1RAB9ACES2 | |
| SCHEMBL1536703 | 0.79 | MAOA (0.56) | ALDH1A1LMNA | |
| SCHEMBL23192702 | 0.78 | KMT2A (0.39) | KMT2AMEN1NPC1RAB9ACES2 | |
| SCHEMBL7193415 | 0.77 | ALDH1A1 (0.44) | KMT2ACES2CES1ALDH1A1LMNA | |
| SCHEMBL28972199 | 0.77 | KMT2A (0.38) | KMT2ACES2CES1ALDH1A1LMNA | |
| SCHEMBL19042193 | 0.75 | L3MBTL1 (0.46) | KMT2ACES2CES1ALDH1A1LMNA | |
| SCHEMBL809922 | 0.75 | KMT2A (0.37) | KMT2AMEN1NPC1RAB9ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3518927-B9 | 1-PHENYLPROPANONE COMPOUNDS AND USE THEREOF | UNIV DEGLI STUDI PADOVA (IT) | 2021-04-07 | — | — | EP | disclosed |
| EP-3518927-B1 | 1-PHENYLPROPANONE COMPOUNDS AND USE THEREOF | UNIV DEGLI STUDI PADOVA (IT) | 2020-08-12 | — | — | EP | disclosed |