Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913096 | 0.98 | TSHR (0.41) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28596049 | 0.97 | TSHR (0.39) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2233573 | 0.78 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28894979 | 0.78 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL211430 | 0.75 | TSHR (0.42) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2233588 | 0.75 | — | — | |
| SCHEMBL27507409 | 0.75 | — | — | |
| SCHEMBL2231431 | 0.74 | TSHR (0.35) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8427879 | 0.74 | SLC6A2 (0.37) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28138890 | 0.74 | TSHR (0.41) | TSHRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |