Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPRC | P08575 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885799 | 0.89 | CA1 (0.53) | ALDH1A1RAB9ACYP3A4MEN1HPGD | |
| SCHEMBL2993382 | 0.85 | CA1 (0.53) | ALDH1A1RAB9ACYP3A4PTPRCMEN1 | |
| SCHEMBL2252533 | 0.85 | CA1 (0.57) | ALDH1A1RAB9ACYP3A4MEN1HPGD | |
| SCHEMBL7451901 | 0.85 | CA1 (0.57) | ALDH1A1RAB9ACYP3A4MEN1HPGD | |
| SCHEMBL8076766 | 0.85 | CA1 (0.57) | ALDH1A1TDP1RAB9ACYP3A4NPC1 | |
| SCHEMBL7786812 | 0.85 | CA1 (0.57) | ALDH1A1RAB9ACYP3A4MEN1HPGD | |
| SCHEMBL30629120 | 0.85 | CA1 (0.57) | ALDH1A1TDP1RAB9ACYP3A4NPC1 | |
| SCHEMBL31087632 | 0.83 | NPC1 (0.78) | ALDH1A1TDP1RAB9ACYP3A4NPC1 | |
| SCHEMBL9019017 | 0.83 | NPC1 (0.78) | ALDH1A1TDP1RAB9ACYP3A4NPC1 | |
| SCHEMBL4645032 | 0.82 | PTPN1 (0.58) | ALDH1A1TDP1RAB9ACYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315895-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | IMMUNEBRIDGE LLC | 2022-10-06 | — | — | US | disclosed |
| WO-2020223517-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | TRANSFUSION HEALTH, LLC (US) | 2020-11-05 | — | — | WO | disclosed |
| US-20200255371-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | IMMUNEBRIDGE LLC | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255371-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | FLI1, MCL1, HCLS1 | ALDH1A1 193/4885TDP1 3727/4885RAB9A 775/4885 |
| US-20220315895-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | MCL1, CD14, ICOS | ALDH1A1 541/4885TDP1 1119/4885RAB9A 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.