Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 3/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13756275 | 0.86 | RXRA (0.47) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL9967840 | 0.85 | KDM1A (0.47) | CYP1A2CYP2C19CYP2C9L3MBTL1MAPT | |
| SCHEMBL12126027 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL12674477 | 0.83 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL24313892 | 0.80 | CYP1A2 (0.54) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL12128991 | 0.80 | MRGPRX4 (0.55) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL22809489 | 0.80 | IDO1 (0.47) | L3MBTL1LMNAMAPTATMPDE2A | |
| SCHEMBL2241258 | 0.80 | L3MBTL1 (0.72) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL16960838 | 0.80 | CYP1A2 (0.54) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA | |
| SCHEMBL1440131 | 0.80 | CYP1A2 (0.54) | CYP1A2CYP2C19CYP2C9L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274101-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-03-15 | — | — | US | disclosed |
| US-11242348-B2 | — | — | 2022-02-08 | — | — | US | disclosed |
| US-20200255439-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255439-A1 | HETEROCYCLIC COMPOUND | MAG, HTT, ACHE | CYP1A2 3217/4885CYP2C19 2935/4885CYP2C9 3156/4885 |
| US-11274101-B2 | Heterocyclic compound | MAG, HTT, ACHE | CYP1A2 3217/4885CYP2C19 2935/4885CYP2C9 3156/4885 |
| US-11242348-B2 | — | MAG, ACHE, GAP43 | CYP1A2 3684/4885CYP2C19 4092/4885CYP2C9 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.