Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336157 | 0.78 | APP (0.33) | APPNOTUMPDE2API4KAPI4K2B | |
| SCHEMBL29268144 | 0.76 | PDE2A (0.39) | APPNOTUMPDE2API4KAPI4K2B | |
| SCHEMBL30567613 | 0.72 | KCNJ1 (0.33) | APPNOTUMALDH1A1 | |
| SCHEMBL22337069 | 0.72 | CYP11B2 (0.33) | APPNOTUM | |
| SCHEMBL29989310 | 0.72 | APP (0.33) | APPNOTUM | |
| Hydrochloric Acid SCHEMBL29268018 | 0.69 | IRAK4 (0.31) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22323133 | 0.67 | PDE1C (0.40) | KMT2AALDH1A1 | |
| SCHEMBL22336937 | 0.65 | PI4KA (0.37) | PDE2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7920028 | 0.65 | CCR1 (0.43) | APPPDE2API4KAPI4K2BPI4K2A | |
| SCHEMBL24597613 | 0.64 | ALDH1A1 (0.33) | APPPDE2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161209-A1 | HERBICIDAL FUSED PYRIDAZINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |