Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336157 | 0.73 | APP (0.33) | APPNOTUM | |
| SCHEMBL22337158 | 0.72 | APP (0.32) | APPNOTUM | |
| SCHEMBL29268144 | 0.72 | PDE2A (0.39) | TP53MAPTAPPNOTUM | |
| SCHEMBL16887703 | 0.71 | TP53 (0.43) | CYP11B2TP53 | |
| SCHEMBL23357368 | 0.70 | ALDH1A1 (0.41) | TP53MAPT | |
| SCHEMBL30711996 | 0.70 | ALDH1A1 (0.41) | TP53MAPT | |
| SCHEMBL30971302 | 0.70 | CYP11B2 (0.32) | CYP11B2TP53MAPTKDM1A | |
| SCHEMBL30711998 | 0.70 | MAPT (0.36) | CYP11B2TP53MAPTKDM1A | |
| SCHEMBL23357465 | 0.70 | MAPT (0.36) | CYP11B2TP53MAPTKDM1A | |
| SCHEMBL31194514 | 0.69 | CTSS (0.40) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161209-A1 | HERBICIDAL FUSED PYRIDAZINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-13 | — | — | WO | disclosed |