Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.31 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759788 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL16678509 | 0.71 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL22276485 | 0.70 | KDM4E (0.52) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL23429123 | 0.66 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL22519156 | 0.66 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL21826411 | 0.65 | GAA (0.64) | ALDH1A1KDM4EHPGDRAB9AGAA | |
| SCHEMBL14572003 | 0.65 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL31415413 | 0.63 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL12146430 | 0.63 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11892541 | 0.63 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163193-A1 | BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-08-13 | — | — | WO | disclosed |