Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.83 |
| ▸ | KDR | P35968 | 7/20 | 0.83 |
| ▸ | RET | P07949 | 3/20 | 0.83 |
| ▸ | LCK | P06239 | 3/20 | 0.81 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.69 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.69 |
| ▸ | FLT1 | P17948 | 2/20 | 0.66 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604741 | 0.91 | EGFR (0.85) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL29515328 | 0.91 | EGFR (1.00) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL1257431 | 0.91 | EGFR (1.00) | EGFRKDRRETLCKRIPK2 | |
| Hydrochloric Acid SCHEMBL5475737 | 0.90 | EGFR (1.00) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL1387182 | 0.89 | EGFR (0.94) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL30891782 | 0.88 | EGFR (0.83) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL20805304 | 0.88 | EGFR (0.77) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL8349430 | 0.88 | EGFR (0.91) | EGFRKDRRETEPHB2FLT1 | |
| Hydrochloric Acid SCHEMBL8807895 | 0.87 | EGFR (0.95) | EGFRKDRRETLCKRIPK2 | |
| SCHEMBL5238437 | 0.85 | EGFR (0.77) | EGFRKDRRETLCKRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |