Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231809 | 0.91 | ACACB (0.38) | ACACBATMAKR1B10AKR1B1DPP4 | |
| SCHEMBL2233299 | 0.88 | PTGER3 (0.42) | ACACBMAOBPPARG | |
| SCHEMBL2233287 | 0.88 | PTGER3 (0.42) | ACACBMAOBPPARG | |
| SCHEMBL2235535 | 0.87 | SMN1; SMN2 (0.38) | ACACBAKR1B10AKR1B1DPP4APP | |
| SCHEMBL2233918 | 0.82 | PSEN1 (0.51) | PPARGPTGESALOX5PSEN1 | |
| SCHEMBL2231986 | 0.82 | RAB9A (0.38) | ACACBATMAKR1B10AKR1B1DPP4 | |
| SCHEMBL2233914 | 0.79 | ACACB (0.41) | ACACBATMMAOBPPARGPTGES | |
| SCHEMBL13582606 | 0.78 | RAB9A (0.41) | ACACBMAOBPPARGTDP1 | |
| SCHEMBL13582608 | 0.78 | RAB9A (0.41) | ACACBMAOBPPARGTDP1 | |
| SCHEMBL13582482 | 0.78 | PTGER3 (0.41) | ACACBMAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |