Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PTGES | O14684 | 4/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231811 | 0.91 | ACACB (0.39) | ACACBPSEN1ALOX5PPARGPTGES | |
| SCHEMBL2235542 | 0.87 | NR4A2 (0.41) | ACACBMAOB | |
| SCHEMBL2233918 | 0.83 | PSEN1 (0.51) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2231990 | 0.82 | RAB9A (0.38) | ACACBPSEN1ALOX5PPARGPTGES | |
| SCHEMBL2233299 | 0.79 | PTGER3 (0.42) | ACACBPPARGACACAMAOB | |
| SCHEMBL2233287 | 0.79 | PTGER3 (0.42) | ACACBPPARGACACAMAOB | |
| SCHEMBL2233912 | 0.79 | ACACB (0.41) | ACACBPSEN1ALOX5PPARGPTGES | |
| SCHEMBL2231815 | 0.78 | PSEN1 (0.51) | PSEN1ALOX5PPARGPTGES | |
| SCHEMBL2231791 | 0.77 | PPARG (0.40) | ACACBPSEN1ALOX5PPARGPTGES | |
| SCHEMBL2233200 | 0.77 | ALOX5 (0.35) | ACACBALOX5PPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |