Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146527 | 0.93 | ADORA3 (0.62) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL313413 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL17889837 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL19485512 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL9945526 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL233209 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL17301042 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL21953578 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL6909853 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 | |
| SCHEMBL29617913 | 0.92 | LMNA (0.72) | ADORA3LMNASLC29A1TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953032-B2 | Cyclic dinucleotides as anticancer agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-03-23 | — | — | US | disclosed |
| US-20200253997-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200253997-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | DPYD, NTPCR, CD38 | ADORA3 1317/4885POLB 32/4885LMNA 1999/4885 |
| US-10953032-B2 | Cyclic dinucleotides as anticancer agents | DPYD, NTPCR, CD38 | ADORA3 1317/4885POLB 32/4885LMNA 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.