Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 9/20 | 0.36 |
| ▸ | ACHE | P22303 | 9/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340327 | 0.72 | KDM4E (0.43) | GAA | |
| SCHEMBL3917191 | 0.68 | DNMT1 (1.00) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL2038233 | 0.65 | DNMT1 (0.64) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL733650 | 0.65 | DNMT1 (0.64) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL10330809 | 0.64 | DNMT1 (0.81) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL7271430 | 0.63 | DNMT1 (0.61) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL9985987 | 0.62 | CA12 (0.48) | GAACA2CA12SMN1; SMN2 | |
| SCHEMBL11290816 | 0.62 | DNMT1 (0.60) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL16693835 | 0.62 | DNMT1 (0.59) | DNMT1G6PDGAABCHEACHE | |
| SCHEMBL29384596 | 0.62 | DNMT1 (0.59) | DNMT1G6PDGAABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | SLC35B2, PPIP5K2, PPA1 | DNMT1 3920/4885G6PD 749/4885GAA 1787/4885 |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | SLC35B2, PPIP5K2, PPA1 | DNMT1 3920/4885G6PD 749/4885GAA 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.