Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.64 |
| ▸ | G6PD | P11413 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 6/20 | 0.52 |
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343468 | 0.90 | DNMT1 (0.59) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL30537780 | 0.86 | DNMT1 (0.55) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL733650 | 0.84 | DNMT1 (0.64) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL17639946 | 0.83 | G6PD (0.53) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL30120630 | 0.83 | DNMT1 (0.52) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL7271430 | 0.82 | DNMT1 (0.61) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL29384596 | 0.80 | DNMT1 (0.59) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL16693835 | 0.80 | DNMT1 (0.59) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL29355952 | 0.80 | DNMT1 (0.59) | DNMT1G6PDGAACA1CA2 | |
| SCHEMBL16471369 | 0.80 | DNMT1 (0.59) | DNMT1G6PDGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590115-B2 | Technologies useful for oligonucleotide preparation | WAVE LIFE SCIENCES LTD. (SG) | 2026-03-31 | — | — | US | disclosed |
| US-20260008806-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD (SG) | 2026-01-08 | — | — | US | disclosed |
| US-12435105-B2 | Technologies for oligonucleotide preparation | WAVE LIFE SCIENCES LTD. (SG) | 2025-10-07 | — | — | US | disclosed |
| US-20240327448-A1 | LITHIUM REAGENTS AND THEIR USES IN SOLID PHASE SYNTHESIS | OLIX US, INC. | 2024-10-03 | — | — | US | disclosed |
| WO-2024173777-A1 | LITHIUM REAGENTS AND THEIR USES IN SOLID PHASE SYNTHESIS | OLIX US, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| US-20230348524-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-02 | — | — | US | disclosed |
| US-20230089442-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-23 | — | — | US | disclosed |
| US-11608355-B2 | Technologies for oligonucleotide preparation | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-21 | — | — | US | disclosed |
| CN-113748116-A | Techniques useful for oligonucleotide preparation | 波涛生命科学有限公司 | 2021-12-03 | — | — | CN | disclosed |
| US-20210309690-A1 | OLIGONUCLEOTIDE SYNTHESIS | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2021-10-07 | — | — | US | disclosed |
| US-6384209-B1 | HIGHLY EFFIENT PROCESS BY CONTACTING OLIGONUCLEOTIDE HAVING INTERNUCLEOSIDE LINKAGE OF A PHOSPHOROUS III ATOM WITH A REAGENT OF DEFINED STRUCTURE; REAGENTS ARE INEXPENSIVE TO MAKE AND STABLE IN STORAGE | AVECIA BIOTECHNOLOGY, INC. (GB) | 2002-05-07 | — | — | US | disclosed |
| WO-2002020544-A1 | PROCESS FOR PREPARING PEPTIDE DERIVATIZED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |
| US-20020010326-A1 | NOVEL SULFURIZING REAGENT 3-PHENYL-1,2,4-DITHIAZOLINE-5-ONE | NITTO DENKO AVECIA, INC. | 2002-01-24 | — | — | US | disclosed |
| US-6096881-A | Sulfur transfer reagents for oligonucleotide synthesis | HYBRIDON, INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0986571-A1 | NOVEL SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON, INC. (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998054198-A9 | NOVEL SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON INC (US) | 1999-04-01 | — | — | WO | disclosed |
| WO-1999003873-A2 | NOVEL SULFURIZING REAGENT 3-PHENYL-1,2,4-DITHIAZOLINE-5-ONE | HYBRIDON, INC. (US) | 1999-01-28 | — | — | WO | disclosed |
| WO-1998054198-A1 | NOVEL SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON, INC. (US) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998049181-A1 | NOVEL SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON, INC. (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998008809-A1 | NOVEL SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON, INC. (US) | 1998-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309690-A1 | OLIGONUCLEOTIDE SYNTHESIS | RNGTT, RTCB, TYMS | DNMT1 163/4885G6PD 811/4885GAA 1590/4885 |
| US-11608355-B2 | Technologies for oligonucleotide preparation | POLRMT, DCLRE1B, RNGTT | DNMT1 131/4885G6PD 4435/4885GAA 687/4885 |
| US-20020010326-A1 | NOVEL SULFURIZING REAGENT 3-PHENYL-1,2,4-DITHIAZOLINE-5-ONE | BPNT1, DNTT, TST | DNMT1 998/4885G6PD 2814/4885GAA 3692/4885 |
| US-20260008806-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | RNGTT, RNMT, NSUN2 | DNMT1 56/4885G6PD 3661/4885GAA 4343/4885 |
| US-12435105-B2 | Technologies for oligonucleotide preparation | POLRMT, DCLRE1B, RNGTT | DNMT1 131/4885G6PD 4435/4885GAA 687/4885 |
| US-20240327448-A1 | LITHIUM REAGENTS AND THEIR USES IN SOLID PHASE SYNTHESIS | POLRMT, NSUN2, RNGTT | DNMT1 116/4885G6PD 2451/4885GAA 2579/4885 |
| US-20230089442-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | POLRMT, DCLRE1B, POLM | DNMT1 103/4885G6PD 4265/4885GAA 786/4885 |
| US-20230348524-A1 | TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION | POLRMT, DCLRE1B, RNGTT | DNMT1 131/4885G6PD 4435/4885GAA 687/4885 |
| US-12590115-B2 | Technologies useful for oligonucleotide preparation | NOP2, RNGTT, NSUN2 | DNMT1 163/4885G6PD 2949/4885GAA 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.