Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22324896 | 0.82 | SLC18A3 (0.41) | ALDH1A1SMN1; SMN2HSD11B1MAP4K1 | |
| SCHEMBL22324860 | 0.82 | DRD2 (0.44) | — | |
| SCHEMBL22324937 | 0.82 | FAAH (0.42) | ALDH1A1 | |
| SCHEMBL22324798 | 0.82 | SLC18A3 (0.41) | ALDH1A1KDM4EHSD11B1IP6K1MAP4K1 | |
| SCHEMBL22340466 | 0.81 | DHFR (0.46) | HSD11B1IP6K1 | |
| SCHEMBL15364610 | 0.81 | TRIM24 (0.61) | TRIM24TRIM33ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22324868 | 0.80 | DRD2 (0.49) | ALDH1A1 | |
| SCHEMBL22324845 | 0.80 | GRM2 (0.44) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22324846 | 0.79 | FAAH (0.47) | ALDH1A1KDM4EHSD11B1IP6K1 | |
| SCHEMBL22324857 | 0.79 | SLC18A3 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163689-A1 | 20-HETE FORMATION INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-13 | — | — | WO | disclosed |