Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | CTSD | P07339 | 1/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18767127 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HPGDCTSDKCNA3NPC1 | |
| SCHEMBL18893131 | 0.83 | L3MBTL1 (0.74) | ALDH1A1HPGDRXFP1CTSDKCNA3 | |
| SCHEMBL30776214 | 0.82 | HPGD (0.68) | ALDH1A1HPGDCTSDKCNA3NPC1 | |
| SCHEMBL28398272 | 0.81 | HPGD (0.66) | ALDH1A1HPGDCTSDKCNA3NPC1 | |
| SCHEMBL2251629 | 0.81 | HPGD (0.70) | ALDH1A1HPGDRXFP1CTSDKCNA3 | |
| SCHEMBL2251625 | 0.81 | HPGD (0.70) | ALDH1A1HPGDRXFP1CTSDKCNA3 | |
| SCHEMBL2792267 | 0.81 | HPGD (0.70) | ALDH1A1HPGDRXFP1CTSDKCNA3 | |
| SCHEMBL29894117 | 0.81 | HPGD (0.70) | ALDH1A1HPGDRXFP1CTSDKCNA3 | |
| SCHEMBL8029750 | 0.80 | HPGD (0.69) | ALDH1A1HPGDRXFP1CTSDKCNA3 | |
| SCHEMBL24801412 | 0.79 | HPGD (0.68) | ALDH1A1HPGDRXFP1CTSDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163236-A1 | TREATING LONG QT SYNDROME | THE GENERAL HOSPITAL CORPORATION (US) | 2020-08-13 | — | — | WO | disclosed |