Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22341873 | 0.82 | P4HTM (0.46) | P4HTMHDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL28294216 | 0.82 | P4HTM (0.50) | P4HTMHDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL24341942 | 0.81 | TDP1 (0.42) | HDAC4PDCD1CD274MAPTNPC1 | |
| SCHEMBL7655050 | 0.78 | HDAC4 (0.44) | P4HTMHDAC4 | |
| SCHEMBL27961398 | 0.77 | TRPV1 (0.59) | TRPV1DGAT1 | |
| SCHEMBL7108522 | 0.77 | SMO (0.40) | HDAC4PDCD1CD274MAPT | |
| SCHEMBL20327068 | 0.77 | MTOR (0.39) | HDAC4 | |
| SCHEMBL28813012 | 0.75 | TRPV1 (0.41) | P4HTMTRPV1PDCD1CD274DGAT1 | |
| SCHEMBL24800710 | 0.74 | HDAC4 (0.34) | HDAC4PDCD1CD274GAA | |
| SCHEMBL25094798 | 0.74 | ESRRG (0.41) | HDAC4TRPV1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| EP-3484878-B1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-19 | — | — | EP | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |