Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14659222 | 0.83 | ALDH1A1 (0.50) | TRPV1 | |
| SCHEMBL27961398 | 0.80 | TRPV1 (0.59) | TRPV1DGAT1 | |
| SCHEMBL14665877 | 0.77 | HSD17B10 (0.44) | PDCD1CD274HSD17B10 | |
| SCHEMBL16246131 | 0.77 | TRPV1 (0.39) | TRPV1HSD17B10P4HTM | |
| SCHEMBL1900631 | 0.77 | PDE7A (0.41) | TRPV1HSD17B10P4HTM | |
| SCHEMBL22341854 | 0.75 | P4HTM (0.44) | TRPV1DGAT1PDCD1CD274P4HTM | |
| SCHEMBL7655038 | 0.74 | PDCD1 (0.44) | PDCD1CD274HSD17B10 | |
| SCHEMBL14658982 | 0.73 | HSD17B10 (0.43) | PDCD1CD274HSD17B10 | |
| SCHEMBL7107855 | 0.73 | HSD17B10 (0.47) | PDCD1CD274HSD17B10 | |
| SCHEMBL25202900 | 0.72 | TRPV1 (0.52) | TRPV1DGAT1SLC2A1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103842357-A | Substituted heteroaromatic pyrazole-containing carboxamide and urea compounds as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-06-04 | — | — | CN | disclosed |