SCHEMBL22343407

SCHEMBL22343407

CC(=O)Oc1cc(C)c(OC(C)=O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.57
ELANE P08246 3/20 0.52
TTR P02766 4/20 0.47
KDM4E B2RXH2 4/20 0.47
MAPT P10636 4/20 0.47
TP53 P04637 2/20 0.47
GAA P10253 2/20 0.47
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 3/20 0.45
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
USP2 O75604 2/20 0.45
ADORA3 P0DMS8 2/20 0.45
ADORA2A P29274 2/20 0.45
ADORA1 P30542 2/20 0.45
ABCC4 O15439 1/20 0.45
LMNA P02545 1/20 0.45
HSP90AA1 P07900 1/20 0.45
CHRM2 P08172 1/20 0.45
HSP90AB1 P08238 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8996376 0.83 TTR (0.51) HTTELANETTRKDM4EMAPT
SCHEMBL5821938 0.82 HTT (0.50) HTTELANETTRKDM4EMAPT
SCHEMBL22324683 0.82 TTR (0.44) HTTELANETTRKDM4EMAPT
SCHEMBL22323640 0.81 MAPT (0.44) HTTELANETTRKDM4EMAPT
SCHEMBL497339 0.81 MAPT (0.60) HTTTTRKDM4EMAPTTP53
SCHEMBL29551111 0.81 MAPT (0.60) HTTTTRKDM4EMAPTTP53
SCHEMBL22343439 0.81 TTR (0.43) HTTELANETTRKDM4EMAPT
SCHEMBL26187355 0.78 ELANE (0.69) HTTELANETTRKDM4EMAPT
SCHEMBL4645309 0.76 SMN1; SMN2 (0.58) HTTELANETTRKDM4EMAPT
SCHEMBL14507724 0.76 HTT (0.59) HTTELANEKDM4EMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220109157-A1 Conducting redox oligomers SJOEDIN MARTIN (SE) 2022-04-07 US disclosed
WO-2020162824-A1 CONDUCTING REDOX OLIGOMERS SJÖDIN MARTIN (SE) 2020-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220109157-A1 Conducting redox oligomers NOX4, CYBB, LPO HTT 1225/4885ELANE 3112/4885TTR 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.