Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234153 | 0.83 | KMT2A (0.37) | BRD4KDM4EALDH1A1NPC1GAA | |
| SCHEMBL2234145 | 0.83 | KMT2A (0.37) | BRD4KDM4EALDH1A1NPC1GAA | |
| SCHEMBL14386531 | 0.76 | ALOX12 (0.71) | ALOX12EPHX2BRD4CACNA1GCACNA1H | |
| SCHEMBL6178932 | 0.74 | SCN9A (0.49) | ALOX12EPHX2BRD4HDAC2HDAC8 | |
| SCHEMBL12345856 | 0.74 | EPHX2 (0.59) | ALOX12EPHX2BRD4CACNA1GCACNA1H | |
| SCHEMBL12345855 | 0.74 | SCN9A (0.49) | ALOX12EPHX2BRD4HDAC2HDAC8 | |
| SCHEMBL3910690 | 0.74 | EPHX2 (0.53) | ALOX12EPHX2BRD4CACNA1GCACNA1H | |
| SCHEMBL17312583 | 0.73 | RIPK1 (0.39) | EPHX2KDM4EALDH1A1NPC1GAA | |
| SCHEMBL17312584 | 0.73 | RIPK1 (0.39) | EPHX2KDM4EALDH1A1NPC1GAA | |
| Hydrochloric Acid SCHEMBL2236123 | 0.73 | EPHX2 (0.58) | ALOX12EPHX2BRD4CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994161-B2 | Derivatives of 2-alkoxy-3,4,5-trihydroxy-alkyl amides, preparation and use thereof, and compositions containing the same | SANOFI-AVENTIS (FR) | 2011-08-09 | — | — | US | disclosed |