Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 8/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29839998 | 0.98 | PIM1 (0.36) | PIM1AXLEPHX2MAPK1KDM5B | |
| SCHEMBL28380619 | 0.73 | CHEK1 (0.38) | PIM1PLAU | |
| SCHEMBL19358234 | 0.73 | AXL (0.49) | PIM1AXLEPHX2MAP4K1 | |
| SCHEMBL16561353 | 0.72 | PIM1 (0.38) | PIM1AXLEPHX2MAPK1KDM5B | |
| Hydrochloric Acid SCHEMBL31576163 | 0.70 | KDM5B (0.43) | PIM1MAPK1KDM5BMAPT | |
| SCHEMBL14983673 | 0.69 | SIGMAR1 (0.44) | PIM1AXLKDM5B | |
| SCHEMBL22344957 | 0.68 | GPR119 (0.43) | — | |
| SCHEMBL29839990 | 0.68 | GPR119 (0.43) | — | |
| SCHEMBL16701022 | 0.67 | PIM1 (0.42) | PIM1AXLEPHX2MAPK1KDM5B | |
| SCHEMBL26242520 | 0.67 | PIM1 (0.39) | PIM1AXLEPHX2MAPK1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110944998-B | Dihydro-pyrrolo-pyridine derivatives | 辉瑞大药厂 | 2022-08-16 | — | — | CN | disclosed |
| US-11198692-B2 | Dihydro-pyrrolo-pyridine derivatives | PFIZER INC. (US) | 2021-12-14 | — | — | US | disclosed |
| US-20200262833-A1 | DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | PFIZER (US) | 2020-08-20 | — | — | US | disclosed |
| CN-110944998-A | Dihydro-pyrrolo-pyridine derivatives | 辉瑞大药厂 | 2020-03-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262833-A1 | DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES | CHRM1, CHRM2, CHRM4 | PIM1 2863/4885AXL 2687/4885EPHX2 683/4885 |
| US-11198692-B2 | Dihydro-pyrrolo-pyridine derivatives | CHRM1, CHRM2, CHRM4 | PIM1 2863/4885AXL 2687/4885EPHX2 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.