Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135180 | 0.81 | MEN1 (0.36) | LCKFYNMEN1KMT2A | |
| SCHEMBL101046 | 0.72 | KMT2A (0.46) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL8027852 | 0.71 | MEN1 (0.45) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2917593 | 0.70 | LCK (0.54) | KDM4EALDH1A1HPGDHSD17B10LCK | |
| SCHEMBL14299277 | 0.70 | MEN1 (0.46) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL136734 | 0.69 | MEN1 (0.44) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL22423635 | 0.69 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL101283 | 0.69 | KMT2A (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL18293533 | 0.69 | MEN1 (0.43) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL16361913 | 0.69 | MEN1 (0.43) | KDM4EALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027618-A2 | FUNCTIONALIZED CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | KDM4E 2687/4885ALDH1A1 1447/4885HPGD 4047/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | KDM4E 2687/4885ALDH1A1 1447/4885HPGD 4047/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | KDM4E 2687/4885ALDH1A1 1447/4885HPGD 4047/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | KDM4E 2687/4885ALDH1A1 1447/4885HPGD 4047/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | KDM4E 2522/4885ALDH1A1 1508/4885HPGD 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.