Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19384703 | 0.88 | RARB (0.60) | LPLLIPGRARBRARARARG | |
| SCHEMBL225580 | 0.86 | LPL (0.47) | LPLLIPGRARBRARARARG | |
| SCHEMBL31028375 | 0.83 | LPL (0.50) | LPLLIPGRARBRARARARG | |
| SCHEMBL1533780 | 0.83 | LPL (0.50) | LPLLIPGRARBRARARARG | |
| SCHEMBL7743235 | 0.82 | LPL (0.45) | LPLLIPGCA1CA2NPC1 | |
| SCHEMBL16038459 | 0.81 | MCL1 (0.49) | LPLLIPGRARBRARARARG | |
| SCHEMBL16258127 | 0.80 | RARB (0.46) | LPLLIPGRARBRARARARG | |
| SCHEMBL14525745 | 0.80 | RARB (0.46) | LPLLIPGRARBRARARARG | |
| SCHEMBL9764255 | 0.80 | RARB (0.46) | LPLLIPGRARBRARARARG | |
| SCHEMBL9253107 | 0.80 | LPL (0.38) | LPLLIPGRARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011920-B | Liquid-crystalline medium comprising thiophene derivatives | 默克专利股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| US-9803140-B2 | Liquid crystal compound and liquid crystal composition | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2017-10-31 | — | — | US | disclosed |
| US-9803140-B2 | Liquid crystal compound and liquid crystal composition | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2017-10-31 | — | — | US | disclosed |
| US-20170101581-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2017-04-13 | — | — | US | disclosed |
| US-20170101581-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2017-04-13 | — | — | US | disclosed |
| US-9315727-B2 | Compound having fluorinated naphthalene structure and liquid crystal composition of the same | DIC Corporation (Tokyo) (JP) | 2016-04-19 | — | — | US | disclosed |
| EP-2598604-B1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| EP-2598604-B1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-20150259599-A1 | COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF THE SAME | DIC CORPORATION (JP) | 2015-09-17 | — | — | US | disclosed |
| US-8906261-B2 | Liquid crystal medium containing thiophene derivatives | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| EP-2398787-B1 | Thiophene derivates and liquid crystal media comprising the same | MERCK PATENT GMBH (DE) | 2013-01-30 | — | — | EP | disclosed |
| WO-2012013281-A1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012013281-A1 | LIQUID CRYSTAL MEDIUM CONTAINING THIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012007096-A1 | LIQUID-CRYSTALLINE MEDIUM WITH STABILIZER | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-05 | — | — | US | disclosed |
| EP-2398787-A1 | THIOPHENE DERIVATES AND LIQUID CRYSTAL MEDIA COMPRISING THE SAME | Merck Patent GmbH (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010099853-A1 | THIOPHENE DERIVATES AND LIQUID CRYSTAL MEDIA COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010099853-A1 | THIOPHENE DERIVATES AND LIQUID CRYSTAL MEDIA COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101581-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION | LBR, CTNND1, CCNT1 | LPL 2260/4885LIPG 2342/4885RARB 1649/4885 |
| US-20120001123-A1 | THIOPHENE DERIVATIVES, AND LC MEDIA COMPRISING SAME | TEC, TPMT, TST | LPL 86/4885LIPG 477/4885RARB 3907/4885 |
| US-20150259599-A1 | COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF THE SAME | TNK1, CTNND1, FLI1 | LPL 1101/4885LIPG 2349/4885RARB 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.