SCHEMBL22346014

SCHEMBL22346014

N#Cc1cccc(-c2cc(-c3ccc(-c4ccccc4)cc3)cc(-c3cc4ccccc4c4ccccc34)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.46
ALDH1A3 P47895 1/20 0.44
MEN1 O00255 4/20 0.43
ALDH1A1 P00352 4/20 0.43
CYP1A2 P05177 4/20 0.43
KMT2A Q03164 4/20 0.43
CYP3A4 P08684 3/20 0.43
CYP2C19 P33261 3/20 0.43
CLK4 Q9HAZ1 3/20 0.43
LMNA P02545 3/20 0.43
HSD17B10 Q99714 3/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 1/20 0.43
PTPN5 P54829 1/20 0.43
XDH P47989 2/20 0.43
SLC22A12 Q96S37 2/20 0.43
GABRA1 P14867 1/20 0.43
GABRG2 P18507 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20903492 0.89 CYP1A2 (0.51) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2
SCHEMBL24596424 0.89 CA1 (0.43) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2
SCHEMBL13170974 0.89 PGR (0.47) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2
SCHEMBL13170978 0.89 PGR (0.47) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2
SCHEMBL13966811 0.89 PGR (0.47) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2
SCHEMBL13170957 0.87 PGR (0.48) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2
SCHEMBL13171014 0.86 CA1 (0.47) MEN1KMT2ATSHRXDHSLC22A12
SCHEMBL13170981 0.86 XDH (0.47) ADORA2AMEN1ALDH1A1KMT2AHSD17B10
SCHEMBL10242223 0.86 CA1 (0.46) ADORA2AMEN1ALDH1A1KMT2AHSD17B10
SCHEMBL13171067 0.86 CA1 (0.45) ADORA2AALDH1A3MEN1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020166630-A1 COMPOUND HAVING BENZAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE 保土谷化学工業株式会社 2020-08-20 WO disclosed