SCHEMBL10242223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14315795	0.95	CA1 (0.45)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL13170981	0.93	XDH (0.47)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL13171014	0.90	CA1 (0.47)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL13192341	0.88	CA1 (0.46)	CA1CA2XDHSLC22A12ALDH1A1
	SCHEMBL23020323	0.87	CA1 (0.45)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL26754199	0.86	CA1 (0.44)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL22346014	0.86	ADORA2A (0.46)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL23020138	0.86	CYP1A2 (0.49)	XDHSLC22A12CYP11B1ALDH1A1HIF1A
	SCHEMBL13170991	0.84	CA1 (0.50)	CA1CA2XDHSLC22A12CYP11B1
	SCHEMBL25038887	0.84	XDH (0.41)	CA1CA2XDHSLC22A12CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.