SCHEMBL2234870

SCHEMBL2234870

CN1CCN(c2ccccc2)C1=O

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.72
NPC1 O15118 1/20 0.72
RAB9A P51151 1/20 0.72
KMT2A Q03164 1/20 0.72
DRD2 P14416 1/20 0.51
DRD3 P35462 1/20 0.51
SIGMAR1 Q99720 1/20 0.48
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
ROCK2 O75116 1/20 0.43
ROCK1 Q13464 1/20 0.43
KDM1A O60341 2/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6362778 0.88 MEN1 (0.61) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL8299963 0.84 MEN1 (0.52) MEN1NPC1RAB9AKMT2AKDM1A
SCHEMBL610584 0.84 NPC1 (1.00) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL15448368 0.82 DRD2 (0.55) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL3577171 0.82 MAPT (0.47) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL182484 0.80 RAB9A (0.45) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL22349847 0.80 DRD2 (0.54) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL19297530 0.80 RAB9A (0.45) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL12362754 0.80 RAB9A (0.45) MEN1NPC1RAB9AKMT2ADRD2
SCHEMBL11659873 0.80 DRD2 (0.54) MEN1NPC1RAB9AKMT2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565550-B2 Polydiene rubbers with functionalized end groups ARLANXEO DEUTSCHLAND GMBH (DE) 2026-03-03 US disclosed
WO-2025242516-A1 BRANCHED DIENE RUBBER ARLANXEO DEUTSCHLAND GMBH (DE) 2025-11-27 WO disclosed
EP-4126562-B1 POLYDIENE RUBBERS WITH FUNCTIONALIZED END GROUPS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-08-13 EP disclosed
US-12371514-B2 1-amino-3-(oxyalkylalkoxysilyl)-2-propanol-terminated diene rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2025-07-29 US disclosed
US-20250115702-A1 MODIFIED DIENE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-04-10 US disclosed
EP-3999552-B1 CARBOXYTERMINATED DIENE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-03-05 EP disclosed
US-20250043041-A1 FUNCTIONALIZED DIENE RUBBERS PREPARED WITH UNSATURATED SILOXANE-BASED COUPLING AGENTS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-02-06 US disclosed
US-20250043040-A1 DIENE RUBBERS PREPARED WITH UNSATURATED SILOXANE-BASED COUPLING AGENTS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-02-06 US disclosed
EP-4476284-A1 MODIFIED DIENE RUBBERS ARLANXEO Deutschland GmbH (DE) 2024-12-18 EP disclosed
EP-4444762-A1 FUNCTIONALIZED DIENE RUBBERS PREPARED WITH UNSATURATED SILOXANE-BASED COUPLING AGENTS ARLANXEO Deutschland GmbH (DE) 2024-10-16 EP disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
WO-2006114371-A1 NOVEL COMPOUNDS FOR TREATING INFLAMMATORY DISEASES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-11-02 WO disclosed
US-6942948-B2 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-13 US disclosed
CN-1215595-C Nonaqueous electrolyte and secondary battery using the same MITSUBISHI CHEM CORP (JP) 2005-08-17 CN disclosed
CN-1465117-A Nonaqueous electrolyte and secondary battery using the same MITSUBISHI CHEM CORP (JP) 2003-12-31 CN disclosed
US-20030165733-A1 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-09-04 US disclosed
EP-1317013-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-04 EP disclosed
EP-0921800-A4 SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL MYERS SQUIBB CO (US) 2000-12-06 EP disclosed
EP-0921800-A1 SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 1999-06-16 EP disclosed
WO-1997029748-A1 SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 1997-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565550-B2 Polydiene rubbers with functionalized end groups MSR1, NR1H3, NR1H2 MEN1 3818/4885NPC1 2152/4885RAB9A 3555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.