Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633244 | 0.91 | L3MBTL1 (0.35) | L3MBTL1ICMTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3509939 | 0.81 | SLC6A2 (0.47) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL25686040 | 0.80 | OPRM1 (0.36) | L3MBTL1ALDH1A1CYP3A4OPRM1 | |
| SCHEMBL2082178 | 0.74 | LMNA (0.42) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL1332923 | 0.72 | SLC6A2 (0.41) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL15908233 | 0.71 | MAOB (0.40) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL12541847 | 0.71 | L3MBTL1 (0.55) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL10168756 | 0.71 | LMNA (0.41) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL2084708 | 0.71 | SLC6A2 (0.40) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL5650431 | 0.71 | SLC6A2 (0.40) | L3MBTL1CHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203007-A1 | PYRIDINYLACETAMIDE DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | X-CHEM GLOBAL HQ | 2023-06-29 | — | — | US | disclosed |
| US-20230203007-A1 | PYRIDINYLACETAMIDE DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | X-CHEM GLOBAL HQ | 2023-06-29 | — | — | US | disclosed |
| US-10745389-B2 | HDAC6 selective inhibitors, preparation method therefor, and application thereof | CSTONE PHARMACEUTICALS (SUZHOU) CO., LTD. (CN) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745389-B2 | HDAC6 selective inhibitors, preparation method therefor, and application thereof | HDAC6, HDAC1, HDAC11 | L3MBTL1 3796/4885CHRNA1 3521/4885CHRNG 4477/4885 |
| US-20230203007-A1 | PYRIDINYLACETAMIDE DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | SCN1A, SCN3A, SCN2A | L3MBTL1 3181/4885CHRNA1 191/4885CHRNG 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.