Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 18/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349396 | 0.87 | MAOB (0.36) | DDR1 | |
| SCHEMBL22349410 | 0.86 | DDR1 (0.36) | DDR1 | |
| SCHEMBL22349438 | 0.86 | DDR1 (0.33) | DDR1 | |
| SCHEMBL22349403 | 0.85 | DDR1 (0.33) | DDR1 | |
| SCHEMBL22349436 | 0.85 | PTGS1 (0.35) | DDR1 | |
| SCHEMBL22349370 | 0.85 | DDR1 (0.37) | DDR1 | |
| SCHEMBL18357969 | 0.85 | DDR1 (0.35) | DDR1 | |
| SCHEMBL22349445 | 0.84 | DDR1 (0.35) | DDR1 | |
| SCHEMBL22349517 | 0.84 | DDR1 (0.34) | DDR1 | |
| SCHEMBL22349400 | 0.84 | ADORA2B (0.35) | DDR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | DDR1 4468/4885CRHR1 3876/4885L3MBTL1 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.