Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349522 | 0.93 | DDR1 (0.32) | DDR1 | |
| SCHEMBL22349444 | 0.91 | DDR1 (0.35) | PTGS2CYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL22349406 | 0.91 | PTGS1 (0.37) | PTGS2CYP1A2ALDH1A1PTGS1PADI4 | |
| SCHEMBL22349517 | 0.91 | DDR1 (0.34) | CYP1A2HSD17B10USP2ALDH1A1DDR1 | |
| SCHEMBL18357978 | 0.90 | KDM4E (0.36) | ALDH1A1DDR1 | |
| SCHEMBL22349369 | 0.89 | DDR1 (0.34) | PTGS2CYP1A2CYP3A4HSD17B10USP2 | |
| SCHEMBL22349438 | 0.89 | DDR1 (0.33) | TRPA1DDR1 | |
| SCHEMBL22349400 | 0.89 | ADORA2B (0.35) | HSD17B10ALDH1A1DDR1TSHRMAPT | |
| SCHEMBL22349445 | 0.89 | DDR1 (0.35) | DDR1 | |
| SCHEMBL22349403 | 0.88 | DDR1 (0.33) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | TRPA1 72/4885PTGS2 586/4885CYP1A2 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.