Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 16/20 | 0.43 |
| ▸ | PTGES | O14684 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 9/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 13/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236531 | 0.89 | ALOX5 (0.43) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL2236518 | 0.88 | ALOX5 (0.43) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL13582205 | 0.77 | KMT2A (0.52) | MEN1KMT2A | |
| SCHEMBL13582228 | 0.77 | KMT2A (0.52) | MEN1KMT2A | |
| SCHEMBL6060200 | 0.74 | ALOX5 (0.49) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL2232569 | 0.74 | MAPT (0.54) | MEN1KMT2AALOX5 | |
| SCHEMBL2235010 | 0.72 | ALOX5 (0.47) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL13103445 | 0.70 | ALOX5 (0.49) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL3437103 | 0.70 | ALOX5 (0.49) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL3437102 | 0.70 | ALOX5 (0.49) | ALOX5PTGESPPARGPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |