Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.43 |
| ▸ | PTGES | O14684 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235014 | 0.88 | MEN1 (0.43) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL2232569 | 0.85 | MAPT (0.54) | ALOX5KDM4EPOLB | |
| SCHEMBL2236515 | 0.79 | THRA (0.40) | ACACBKDM4EPOLB | |
| SCHEMBL2236512 | 0.78 | APP (0.50) | ACACBKDM4E | |
| SCHEMBL2236531 | 0.77 | ALOX5 (0.43) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL13582057 | 0.77 | KDM4E (0.44) | ACACBKDM4EPOLB | |
| SCHEMBL13582053 | 0.77 | KDM4E (0.44) | ACACBKDM4EPOLB | |
| SCHEMBL2232581 | 0.74 | ALOX5 (0.42) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL2232408 | 0.72 | ALOX5 (0.47) | ALOX5PTGESPPARGPSEN1 | |
| SCHEMBL13742644 | 0.71 | ACACB (0.45) | ACACBKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093524-A1 | DI - SUBSTITUTED PYRIDINE DERIVATIVES AS ANTICANCERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |