Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951371 | 0.88 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL26622753 | 0.85 | L3MBTL1 (0.49) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL27901467 | 0.82 | L3MBTL1 (0.53) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL24608608 | 0.82 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL17385332 | 0.81 | MAPT (0.50) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL13723406 | 0.80 | L3MBTL1 (0.68) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL13254189 | 0.80 | MEN1 (0.55) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL3977038 | 0.79 | L3MBTL1 (0.44) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL16093363 | 0.78 | L3MBTL1 (0.50) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT | |
| SCHEMBL2054328 | 0.78 | L3MBTL1 (0.50) | HSP90AA1HSP90AB1NPBWR1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161835-B2 | Compounds and their use for reducing uric acid levels | ACQUIST LLC (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200339545-A1 | Compounds And Their Use For Reducing Uric Acid Levels | ACQUIST LLC (US) | 2020-10-29 | — | — | US | disclosed |
| US-10752613-B2 | Compounds and their use for reducing uric acid levels | ACQUIST LLC (US) | 2020-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339545-A1 | Compounds And Their Use For Reducing Uric Acid Levels | XDH, OAT, PON1 | HSP90AA1 3690/4885HSP90AB1 4070/4885NPBWR1 3149/4885 |
| US-11161835-B2 | Compounds and their use for reducing uric acid levels | XDH, OAT, PON1 | HSP90AA1 3690/4885HSP90AB1 4070/4885NPBWR1 3149/4885 |
| US-10752613-B2 | Compounds and their use for reducing uric acid levels | XDH, OAT, PON1 | HSP90AA1 3690/4885HSP90AB1 4070/4885NPBWR1 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.