Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.45 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.45 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22353046 | 0.89 | ROCK2 (0.48) | NPC1RAB9ACLK2PRKXCAMK2D | |
| SCHEMBL19577054 | 0.86 | CLK2 (0.44) | NPC1RAB9ACLK2PRKXCAMK2D | |
| SCHEMBL29716971 | 0.83 | P2RX4 (0.56) | LMNAKCNJ5KCNJ3KCNJ6ALDH1A1 | |
| SCHEMBL19576958 | 0.83 | P2RX4 (0.56) | LMNAKCNJ5KCNJ3KCNJ6ALDH1A1 | |
| SCHEMBL22353212 | 0.80 | KCNJ5 (0.49) | CLK2PRKXCAMK2DPKN2CLK4 | |
| SCHEMBL22353164 | 0.79 | KCNJ5 (0.49) | CLK2PRKXCAMK2DPKN2CLK4 | |
| SCHEMBL19576914 | 0.79 | ROCK2 (0.46) | CLK2PRKXCAMK2DPKN2CLK4 | |
| SCHEMBL22353216 | 0.76 | ROCK2 (0.50) | CLK2PRKXCAMK2DPKN2CLK4 | |
| SCHEMBL22353039 | 0.76 | ROCK2 (0.44) | NPC1RAB9ACLK2PRKXCAMK2D | |
| SCHEMBL22894150 | 0.76 | KCNJ5 (0.55) | CLK2PRKXCAMK2DPKN2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458443-B1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma AG (DE) | 2020-08-19 | — | — | EP | disclosed |