Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 7/20 | 0.55 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.55 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 9/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | PRKX | P51817 | 1/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32664293 | 0.79 | KCNJ5 (0.61) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL22353068 | 0.79 | KCNJ5 (0.47) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL19552065 | 0.79 | P2RX4 (0.71) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL29718827 | 0.79 | P2RX4 (0.71) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL22353212 | 0.78 | KCNJ5 (0.49) | KCNJ5KCNJ3KCNJ6P2RX4CLK2 | |
| SCHEMBL24686671 | 0.78 | KCNJ5 (0.50) | KCNJ5KCNJ3KCNJ6P2RX4CLK2 | |
| SCHEMBL24686375 | 0.78 | P2RX4 (0.52) | KCNJ5KCNJ3KCNJ6MEN1KMT2A | |
| SCHEMBL19577034 | 0.78 | ROCK2 (0.47) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL24685908 | 0.77 | KCNJ5 (0.61) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL24687034 | 0.77 | KCNJ5 (0.61) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763704-A1 | AROMATIC SULFONAMIDE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2021-01-13 | — | — | EP | disclosed |