Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233887 | 0.89 | ALDH1A1 (0.35) | NOTUMSRD5A1ALDH1A1GABRG2GABRB3 | |
| SCHEMBL2234063 | 0.82 | KCNJ1 (0.33) | ALDH1A1KDM4EGABRG2GABRB3GABRA5 | |
| SCHEMBL2234596 | 0.81 | GABRG2 (0.34) | SRD5A1ALDH1A1KDM4EGABRG2GABRB3 | |
| SCHEMBL2234603 | 0.81 | GABRG2 (0.34) | SRD5A1ALDH1A1KDM4EGABRG2GABRB3 | |
| SCHEMBL2234469 | 0.80 | SRD5A1 (0.40) | SRD5A1ALDH1A1KDM4EGABRG2GABRB3 | |
| SCHEMBL10006103 | 0.78 | GABRG2 (0.41) | NOTUMALDH1A1GABRG2GABRB3GABRA5 | |
| SCHEMBL2235144 | 0.75 | HRH3 (0.48) | SRD5A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL2234256 | 0.75 | NOTUM (0.38) | NOTUMSRD5A1ALDH1A1KDM4EGABRG2 | |
| SCHEMBL10006128 | 0.75 | GABRG2 (0.39) | NOTUMGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL12255864 | 0.75 | CPB2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213143-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2361910-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213143-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | TAF1, TAF5, TAF11 | NOTUM 547/4885SRD5A1 1412/4885ALDH1A1 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.