Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540183 | 0.85 | MAPK1 (0.35) | MAPK1HIF1A | |
| SCHEMBL17885030 | 0.84 | CES2 (0.32) | MAPK1HIF1A | |
| SCHEMBL14879869 | 0.84 | MAPK1 (0.34) | MAPK1HIF1A | |
| SCHEMBL1597489 | 0.83 | MAPK1 (0.39) | LMNAHSD17B10MAPK1HIF1A | |
| SCHEMBL14879917 | 0.80 | LATS1 (0.32) | — | |
| SCHEMBL16731833 | 0.77 | POLB (0.40) | MAPK1HIF1A | |
| SCHEMBL17918249 | 0.76 | MAPK1 (0.30) | MAPK1HIF1A | |
| SCHEMBL15601874 | 0.75 | — | — | |
| SCHEMBL16360730 | 0.74 | MAPK1 (0.41) | MAPK1HIF1A | |
| SCHEMBL12561788 | 0.74 | THRB (0.38) | LMNAHSD17B10MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200261590-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200261590-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | F8, F9, F13A1 | LMNA 1107/4885HSD17B10 2606/4885MAPK1 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.