Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540183 | 0.87 | MAPK1 (0.35) | MAPK1HIF1A | |
| SCHEMBL17885030 | 0.86 | CES2 (0.32) | MAPK1HIF1A | |
| SCHEMBL1597489 | 0.84 | MAPK1 (0.39) | MAPK1HIF1ASMN1; SMN2 | |
| SCHEMBL22353307 | 0.84 | LMNA (0.33) | MAPK1HIF1A | |
| SCHEMBL14879917 | 0.81 | LATS1 (0.32) | — | |
| SCHEMBL16731833 | 0.79 | POLB (0.40) | MAPK1HIF1A | |
| SCHEMBL25946810 | 0.78 | SMN1; SMN2 (0.38) | HIF1ASMN1; SMN2PTGDR2 | |
| SCHEMBL14963629 | 0.78 | TSHR (0.41) | MAPK1HIF1ASMN1; SMN2PTGS1 | |
| SCHEMBL25946759 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2PTGDR2PTGS1 | |
| SCHEMBL17918249 | 0.77 | MAPK1 (0.30) | MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760639-B1 | ZWITTERIONIC POLYMERS FOR USE AS CONJUGATES WITH FACTOR VIII | KODIAK SCIENCES INC (US) | 2025-10-22 | — | — | EP | disclosed |
| US-12214044-B2 | Factor VIII zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2025-02-04 | — | — | US | disclosed |
| US-20230173081-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. | 2023-06-08 | — | — | US | disclosed |
| US-11590235-B2 | Factor VIII zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2023-02-28 | — | — | US | disclosed |
| EP-3207128-B1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2022-07-27 | — | — | EP | disclosed |
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | KODIAK SCIENCES INC. (US) | 2021-07-27 | — | — | US | disclosed |
| EP-3760639-A1 | ZWITTERIONIC POLYMER CONJUGATES | Kodiak Sciences Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20200261590-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. | 2020-08-20 | — | — | US | disclosed |
| EP-3041513-B1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-3207128-A2 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | Kodiak Sciences Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| US-20160199501-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. | 2016-07-14 | — | — | US | disclosed |
| EP-3041513-A2 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | Kodiak Sciences Inc. (US) | 2016-07-13 | — | — | EP | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS, LLC | 2016-06-30 | — | — | US | disclosed |
| WO-2016061562-A2 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | KODIAK SCIENCES INC. (US) | 2016-04-21 | — | — | WO | disclosed |
| WO-2015035342-A2 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | OLIGASIS LLC (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2013059137-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | OLIGASIS (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2013059137-A1 | HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS | OLIGASIS (US) | 2013-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173081-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | F8, F9, F13A1 | MAPK1 4637/4885HIF1A 3031/4885SMN1; SMN2 3310/4885 |
| US-20160184445-A1 | BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES | BCHE, ACHE, FCER2 | MAPK1 4777/4885HIF1A 4866/4885SMN1; SMN2 3434/4885 |
| US-11071771-B2 | Butyrylcholinesterase zwitterionic polymer conjugates | BCHE, ACHE, FCER2 | MAPK1 4777/4885HIF1A 4866/4885SMN1; SMN2 3434/4885 |
| US-12214044-B2 | Factor VIII zwitterionic polymer conjugates | F8, F9, F13A1 | MAPK1 4637/4885HIF1A 3031/4885SMN1; SMN2 3310/4885 |
| US-20200261590-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | F8, F9, F13A1 | MAPK1 4637/4885HIF1A 3031/4885SMN1; SMN2 3310/4885 |
| US-20160199501-A1 | FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES | F8, F9, F13A1 | MAPK1 4637/4885HIF1A 3031/4885SMN1; SMN2 3310/4885 |
| US-11590235-B2 | Factor VIII zwitterionic polymer conjugates | F8, F9, F13A1 | MAPK1 4637/4885HIF1A 3031/4885SMN1; SMN2 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.