Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | RRM1 | P23921 | 1/20 | 0.54 |
| ▸ | RRM2 | P31350 | 1/20 | 0.54 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726315 | 1.00 | KMT2A (1.00) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL6814454 | 0.85 | KMT2A (0.74) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL132620 | 0.82 | ALDH1A1 (1.00) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL23120126 | 0.82 | KMT2A (0.70) | KMT2AALDH1A1GAALMNAMAPT | |
| SCHEMBL2235398 | 0.81 | GAA (1.00) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL9470190 | 0.80 | ALDH1A1 (0.94) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL8956322 | 0.80 | ALDH1A1 (0.94) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL6814445 | 0.80 | KMT2A (0.66) | KMT2AALDH1A1GAALMNAMAOA | |
| SCHEMBL7098404 | 0.80 | TP53 (0.68) | KMT2AALDH1A1CYP3A4HSD17B10LMNA | |
| SCHEMBL5452814 | 0.79 | KMT2A (0.64) | KMT2AALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-20140031547-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODE-GENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED | 2014-01-30 | — | — | US | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-4048333-A | Method for treating a picorna virus infection | MEDIZINSKA AKADEMIA (BG) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031547-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODE-GENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1G3 | KMT2A 1033/4885ALDH1A1 2473/4885CYP3A4 4042/4885 |
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1D | KMT2A 810/4885ALDH1A1 2638/4885CYP3A4 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.