Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.67 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.65 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.63 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.63 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.63 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.63 |
| ▸ | LDHA | P00338 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.63 |
| ▸ | FBP1 | P09467 | 1/20 | 0.63 |
| ▸ | SRC | P12931 | 1/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.63 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744184 | 0.90 | ADORA1 (0.66) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL9387983 | 0.88 | ADORA1 (0.66) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL1434032 | 0.87 | ADORA1 (0.72) | ADORA1P2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL6905464 | 0.87 | ADORA1 (0.72) | ADORA1P2RY1DNPH1PRKAB2TRPM2 | |
| SCHEMBL441535 | 0.87 | ABCB1 (0.77) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL11644877 | 0.87 | ABCB1 (0.77) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL1757017 | 0.86 | ADORA1 (0.73) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL19859780 | 0.86 | ADORA1 (0.73) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL10275990 | 0.85 | GSK3A (0.64) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 | |
| SCHEMBL7925039 | 0.85 | HSP90B1 (0.70) | GSK3ARPS6KA3MAPK14ADORA1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784556-B | Thiocarbon-protecting groups for rna synthesis | AGILENT TECHNOLOGIES INC | 2014-07-09 | — | — | CN | disclosed |
| US-8202983-B2 | Thiocarbon-protecting groups for RNA synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-7999087-B2 | While still containing silyl group, these new protecting groups can be introduced selectively in high yielding reaction and not be subject to isomerization during introduction or deprotection; efficient coupling reaction when synthesizing RNA | AGILENT TECHNOLOGIES, INC. (US) | 2011-08-16 | — | — | US | disclosed |