Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.66 |
| ▸ | GSK3A | P49840 | 2/20 | 0.65 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.61 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.61 |
| ▸ | GAPDH | P04406 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | STAT6 | P42226 | 1/20 | 0.61 |
| ▸ | PI4KA | P42356 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.61 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235451 | 0.90 | GSK3A (0.67) | ADORA1GSK3ARPS6KA3MAPK14SMN1; SMN2 | |
| SCHEMBL1434032 | 0.88 | ADORA1 (0.72) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL6905464 | 0.88 | ADORA1 (0.72) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL9387983 | 0.85 | ADORA1 (0.66) | ADORA1GSK3ARPS6KA3MAPK14SMN1; SMN2 | |
| SCHEMBL11644877 | 0.84 | ABCB1 (0.77) | ADORA1GSK3ARPS6KA3MAPK14SMN1; SMN2 | |
| SCHEMBL441535 | 0.84 | ABCB1 (0.77) | ADORA1GSK3ARPS6KA3MAPK14SMN1; SMN2 | |
| SCHEMBL1757017 | 0.83 | ADORA1 (0.73) | ADORA1GSK3ARPS6KA3MAPK14SMN1; SMN2 | |
| SCHEMBL19859780 | 0.83 | ADORA1 (0.73) | ADORA1GSK3ARPS6KA3MAPK14SMN1; SMN2 | |
| SCHEMBL2835895 | 0.82 | METTL3 (0.65) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL2835899 | 0.82 | METTL3 (0.65) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |