Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355309 | 0.82 | PTPN1 (0.52) | MEN1KMT2AALDH1A1HPGDPTPN1 | |
| SCHEMBL22355188 | 0.80 | FOLH1 (0.42) | KMT2A | |
| SCHEMBL22355228 | 0.79 | PPARA (0.54) | MEN1KMT2AALDH1A1HPGDPPARA | |
| SCHEMBL22355227 | 0.79 | PPARA (0.54) | MEN1KMT2AALDH1A1HPGDPPARA | |
| SCHEMBL27387111 | 0.79 | ACE (0.55) | MEN1KMT2AALDH1A1HPGDFAP | |
| SCHEMBL7717865 | 0.79 | ACE (0.55) | MEN1KMT2AALDH1A1HPGDFAP | |
| SCHEMBL28711261 | 0.79 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1HPGDCCKBR | |
| SCHEMBL28711262 | 0.79 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1HPGDCCKBR | |
| SCHEMBL20885316 | 0.78 | L3MBTL1 (0.38) | KMT2AALDH1A1OPRK1 | |
| SCHEMBL19177339 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1HPGDCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167831-A1 | METHOD OF PREPARING A DON PRODRUG FROM L-GLUTAMIC ACID | DRACEN PHARMACEUTICALS, INC. (US) | 2020-08-20 | — | — | WO | disclosed |