Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086263 | 0.87 | L3MBTL1 (0.37) | CTSKCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17173874 | 0.81 | CYP2D6 (0.36) | CTSKCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22355214 | 0.80 | LMNA (0.34) | CTSKCYP2D6CYP1A2KMT2ACA1 | |
| SCHEMBL13876903 | 0.80 | MEN1 (0.40) | CTSKCYP2D6KMT2AP2RY12HDAC3 | |
| SCHEMBL17178074 | 0.80 | CYP2D6 (0.34) | CTSKCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18575864 | 0.80 | MEN1 (0.40) | CTSKCYP2D6KMT2AP2RY12HDAC3 | |
| SCHEMBL23901540 | 0.79 | CTSK (0.33) | CTSKCYP2D6CYP1A2CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL28163206 | 0.79 | MEN1 (0.39) | CTSKCYP2D6KMT2AP2RY12HDAC3 | |
| SCHEMBL13711118 | 0.79 | CTSK (0.33) | CTSKCYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22355225 | 0.78 | L3MBTL1 (0.39) | CTSKCYP2D6CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167831-A1 | METHOD OF PREPARING A DON PRODRUG FROM L-GLUTAMIC ACID | DRACEN PHARMACEUTICALS, INC. (US) | 2020-08-20 | — | — | WO | disclosed |