Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23047655 | 0.87 | POLRMT (0.49) | POLRMTP2RY2P2RY1 | |
| SCHEMBL19223073 | 0.85 | POLRMT (0.41) | POLRMTALDH1A1TRPM2P2RY12P2RY2 | |
| SCHEMBL23034475 | 0.85 | POLRMT (0.41) | POLRMTALDH1A1TRPM2P2RY12P2RY2 | |
| SCHEMBL10154324 | 0.84 | CYP3A4 (0.40) | RIPK1 | |
| SCHEMBL10154323 | 0.83 | CYP3A4 (0.46) | RIPK1 | |
| SCHEMBL24119305 | 0.81 | CYP3A4 (0.38) | RIPK1 | |
| SCHEMBL26001843 | 0.80 | TMPRSS2 (0.40) | POLRMTALDH1A1TRPM2P2RY12P2RY2 | |
| SCHEMBL24790485 | 0.80 | PIK3CD (0.35) | POLRMTTNK2RIPK1 | |
| SCHEMBL20878443 | 0.80 | TMPRSS2 (0.45) | POLRMTTRPM2P2RY12P2RY2 | |
| SCHEMBL17722662 | 0.80 | TMPRSS2 (0.45) | POLRMTTRPM2P2RY12P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3695844-A1 | METHODS FOR TREATING NIPAH VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2020-08-19 | — | — | EP | disclosed |