Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791277 | 0.91 | POLRMT (0.32) | POLRMTRIPK1TMPRSS2 | |
| SCHEMBL807426 | 0.85 | ADORA2A (0.35) | POLRMTRIPK1TMPRSS2TNK2 | |
| SCHEMBL24791752 | 0.84 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL24791023 | 0.83 | RIPK1 (0.32) | RIPK1DOT1L | |
| SCHEMBL24312549 | 0.82 | POLRMT (0.35) | PIK3CDPOLRMTRIPK1TMPRSS2DOT1L | |
| SCHEMBL23047655 | 0.81 | POLRMT (0.49) | POLRMT | |
| SCHEMBL24917146 | 0.80 | TSHR (0.35) | PIK3CDPOLRMT | |
| SCHEMBL22355504 | 0.80 | POLRMT (0.38) | POLRMTRIPK1TNK2 | |
| SCHEMBL24790934 | 0.80 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL24790430 | 0.80 | RIPK1 (0.32) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |