SCHEMBL22355514

SCHEMBL22355514

CCCCC1(CCCC)c2ccccc2-c2ccc(/C(CCC3CCCCC3)=N/OC(=O)CC)cc21

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ MAPT P10636 4/20 0.36
▸ PDK2 Q15119 4/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28403051 0.83 PDK2 (0.41) PDK2
SCHEMBL24858669 0.83 MEN1 (0.39) MEN1KMT2AL3MBTL1TDP1SMN1; SMN2
SCHEMBL24490441 0.81 PDK2 (0.35) MEN1KMT2AL3MBTL1TDP1SMN1; SMN2
SCHEMBL22355444 0.81 POLB (0.37) SMN1; SMN2NPC1RAB9AMAPTPDK2
SCHEMBL23552647 0.80 CNR2 (0.38) L3MBTL1
SCHEMBL22497434 0.80 MAPT (0.46) MEN1KMT2AL3MBTL1TDP1SMN1; SMN2
SCHEMBL31747787 0.80 MAPT (0.46) MEN1KMT2AL3MBTL1TDP1SMN1; SMN2
SCHEMBL29317161 0.80 PDK2 (0.36) MEN1KMT2AL3MBTL1TDP1PDK2
SCHEMBL18235857 0.78 PDK2 (0.37) PDK2
SCHEMBL29316858 0.77 MEN1 (0.40) MEN1KMT2AL3MBTL1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11054743-B2 Fluorene polyfunctional photoinitiator and preparation and use thereof, and photosensitive resin composition containing fluorene photoinitiator and use thereof CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2021-07-06 — — US disclosed
EP-3392232-B1 FLUORENE MULTIFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-02-17 — — EP disclosed
US-20200264508-A1 FLUORENE POLYFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2020-08-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11054743-B2 Fluorene polyfunctional photoinitiator and preparation and use thereof, and photosensitive resin composition containing fluorene photoinitiator and use thereof RARA, RARG, PFAS MEN1 4487/4885KMT2A 1239/4885L3MBTL1 2449/4885
US-20200264508-A1 FLUORENE POLYFUNCTIONAL PHOTOINITIATOR AND PREPARATION AND USE THEREOF, AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING FLUORENE PHOTOINITIATOR AND USE THEREOF RARA, RARG, PFAS MEN1 4487/4885KMT2A 1239/4885L3MBTL1 2449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback